Pubmed:
https://pubmed.ncbi.nlm.nih.gov/?term=ralph%20Neum%C3%BCller%20OR%20ralph%20neumueller&sort=date
Google Scholar:
(DE) German:
https://scholar.google.de/citations?user=t9nWMEEAAAAJ&hl=de
(EN) English:
https://scholar.google.de/citations?user=t9nWMEEAAAAJ&hl=en
Peer reviewed Journals:
25: Hoffmann T, Hörmann A, Corcokovic M, Zmajkovic J, Hinterndorfer M, Salkanovic J, Spreitzer F, Köferle A, Gitschtaler K, Popa A, Oberndorfer S, Andersch F, Schaefer M, Fellner M, Budano N, Ruppert JG, Chetta P, Wurm M, Zuber J, Neumüller RA. Precision RNAi using synthetic shRNAmir target sites. Elife. 2023 Aug 8;12:RP84792. doi: 10.7554/eLife.84792. PMID: 37552050; PMCID: PMC10409502.
24: Wilding B, Scharn D, Böse D, Baum A, Santoro V, Chetta P, Schnitzer R, Botesteanu DA, Reiser C, Kornigg S, Knesl P, Hörmann A, Köferle A, Corcokovic M, Lieb S, Scholz G, Bruchhaus J, Spina M, Balla J, Peric-Simov B, Zimmer J, Mitzner S, Fett TN, Beran A, Lamarre L, Gerstberger T, Gerlach D, Bauer M, Bergner A, Schlattl A, Bader G, Treu M, Engelhardt H, Zahn S, Fuchs JE, Zuber J, Ettmayer P, Pearson M, Petronczki M, Kraut N, McConnell DB, Solca F, Neumüller RA. Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling. Nat Cancer. 2022 Jul;3(7):821-836. doi: 10.1038/s43018-022-00412-y. Epub 2022 Jul 26. PMID: 35883003.
23: Köferle A, Schlattl A, Hörmann A, Thatikonda V, Popa A, Spreitzer F, Ravichandran MC, Supper V, Oberndorfer S, Puchner T, Wieshofer C, Corcokovic M, Reiser C, Wöhrle S, Popow J, Pearson M, Martinez J, Weitzer S, Mair B, Neumüller RA. Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes. Cell Rep. 2022 Apr 12;39(2):110636. doi: 10.1016/j.celrep.2022.110636. PMID: 35417719.
22: Ehrenhöfer-Wölfer K, Puchner T, Schwarz C, Rippka J, Blaha-Ostermann S, Strobl U, Hörmann A, Bader G, Kornigg S, Zahn S, Sommergruber W, Schweifer N, Zichner T, Schlattl A, Neumüller RA, Shi J, Vakoc CR, Kögl M, Petronczki M, Kraut N, Pearson MA, Wöhrle S. SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines. Sci Rep. 2019 Aug 12;9(1):11661. doi: 10.1038/s41598-019-48152-x. PMID: 31406271; PMCID: PMC6691015.
21: Böttcher J, Dilworth D, Reiser U, Neumüller RA, Schleicher M, Petronczki M, Zeeb M, Mischerikow N, Allali-Hassani A, Szewczyk MM, Li F, Kennedy S, Vedadi M, Barsyte-Lovejoy D, Brown PJ, Huber KVM, Rogers CM, Wells CI, Fedorov O, Rumpel K, Zoephel A, Mayer M, Wunberg T, Böse D, Zahn S, Arnhof H, Berger H, Reiser C, Hörmann A, Krammer T, Corcokovic M, Sharps B, Winkler S, Häring D, Cockcroft XL, Fuchs JE, Müllauer B, Weiss-Puxbaum A, Gerstberger T, Boehmelt G, Vakoc CR, Arrowsmith CH, Pearson M, McConnell DB. Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Nat Chem Biol. 2019 Aug;15(8):822-829. doi: 10.1038/s41589-019-0310-x. Epub 2019 Jul 8. PMID: 31285596.
20: Lieb S, Blaha-Ostermann S, Kamper E, Rippka J, Schwarz C, Ehrenhöfer-Wölfer K, Schlattl A, Wernitznig A, Lipp JJ, Nagasaka K, van der Lelij P, Bader G, Koi M, Goel A, Neumüller RA, Peters JM, Kraut N, Pearson MA, Petronczki M, Wöhrle S. Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells. Elife. 2019 Mar 25;8:e43333. doi: 10.7554/eLife.43333. PMID: 30910006; PMCID: PMC6435321.
19: Hörmann A, Hopfgartner B, Köcher T, Corcokovic M, Krammer T, Reiser C, Bader G, Shi J, Ehrenhöfer K, Wöhrle S, Schweifer N, Vakoc CR, Kraut N, Pearson M, Petronczki M, Neumüller RA. RIOK1 kinase activity is required for cell survival irrespective of <i>MTAP</i> status. Oncotarget. 2018 Jun 19;9(47):28625-28637. doi: 10.18632/oncotarget.25586. PMID: 29983885; PMCID: PMC6033344.
18: Wissel S, Harzer H, Bonnay F, Burkard TR, Neumüller RA, Knoblich JA. Time- resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop. J Cell Biol. 2018 Sep 3;217(9):3285-3300. doi: 10.1083/jcb.201711167. Epub 2018 Jun 29. PMID: 29959232; PMCID: PMC6123005.
17: Wissel S, Kieser A, Yasugi T, Duchek P, Roitinger E, Gokcezade J, Steinmann V, Gaul U, Mechtler K, Förstemann K, Knoblich JA, Neumüller RA. A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function. G3 (Bethesda). 2016 Aug 9;6(8):2467-78. doi: 10.1534/g3.116.028571. PMID: 27280787; PMCID: PMC4978900.
16: Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim HS, Miller A, Housden A, Foos M, Randkelv S, Kelley C, Namgyal P, Villalta C, Liu LP, Jiang X, Huan-Huan Q, Wang X, Fujiyama A, Toyoda A, Ayers K, Blum A, Czech B, Neumuller R, Yan D, Cavallaro A, Hibbard K, Hall D, Cooley L, Hannon GJ, Lehmann R, Parks A, Mohr SE, Ueda R, Kondo S, Ni JQ, Perrimon N. The Transgenic RNAi Project at Harvard Medical School: Resources and Validation. Genetics. 2015 Nov;201(3):843-52. doi: 10.1534/genetics.115.180208. Epub 2015 Aug 28. PMID: 26320097; PMCID: PMC4649654.
15: Zeng X, Han L, Singh SR, Liu H, Neumüller RA, Yan D, Hu Y, Liu Y, Liu W, Lin X, Hou SX. Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila. Cell Rep. 2015 Feb 24;10(7):1226-38. doi: 10.1016/j.celrep.2015.01.051. Epub 2015 Feb 19. PMID: 25704823; PMCID: PMC4420031.
14: Mohr SE, Smith JA, Shamu CE, Neumüller RA, Perrimon N. RNAi screening comes of age: improved techniques and complementary approaches. Nat Rev Mol Cell Biol. 2014 Sep;15(9):591-600. doi: 10.1038/nrm3860. PMID: 25145850; PMCID: PMC4204798.
13: Markstein M, Dettorre S, Cho J, Neumüller RA, Craig-Müller S, Perrimon N. Systematic screen of chemotherapeutics in Drosophila stem cell tumors. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4530-5. doi: 10.1073/pnas.1401160111. Epub 2014 Mar 10. PMID: 24616500; PMCID: PMC3970492.
12: Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, Cooley L, Perrimon N. A regulatory network of Drosophila germline stem cell self-renewal. Dev Cell. 2014 Feb 24;28(4):459-73. doi: 10.1016/j.devcel.2014.01.020. PMID: 24576427; PMCID: PMC3998650.
11: Vinayagam A, Zirin J, Roesel C, Hu Y, Yilmazel B, Samsonova AA, Neumüller RA, Mohr SE, Perrimon N. Integrating protein-protein interaction networks with phenotypes reveals signs of interactions. Nat Methods. 2014 Jan;11(1):94-9. doi: 10.1038/nmeth.2733. Epub 2013 Nov 17. PMID: 24240319; PMCID: PMC3877743.
10: Neumüller RA, Gross T, Samsonova AA, Vinayagam A, Buckner M, Founk K, Hu Y, Sharifpoor S, Rosebrock AP, Andrews B, Winston F, Perrimon N. Conserved regulators of nucleolar size revealed by global phenotypic analyses. Sci Signal. 2013 Aug 20;6(289):ra70. doi: 10.1126/scisignal.2004145. PMID: 23962978; PMCID: PMC3964804.
9: Neumüller RA, Wirtz-Peitz F, Lee S, Kwon Y, Buckner M, Hoskins RA, Venken KJ, Bellen HJ, Mohr SE, Perrimon N. Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 2012 Mar;190(3):931-40. doi: 10.1534/genetics.111.136465. Epub 2011 Dec 14. PMID: 22174071; PMCID: PMC3296255.
8: Neumüller RA, Richter C, Fischer A, Novatchkova M, Neumüller KG, Knoblich JA. Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell. 2011 May 6;8(5):580-93. doi: 10.1016/j.stem.2011.02.022. PMID: 21549331; PMCID: PMC3093620.
7: Neumüller RA, Perrimon N. Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. Wiley Interdiscip Rev Syst Biol Med. 2011 Jul-Aug;3(4):471-8. doi: 10.1002/wsbm.127. Epub 2010 Dec 31. PMID: 21197652; PMCID: PMC3560415.
6: Neumüller RA, Knoblich JA. Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes Dev. 2009 Dec 1;23(23):2675-99. doi: 10.1101/gad.1850809. PMID: 19952104; PMCID: PMC2788323.
5: Neumüller RA, Knoblich JA. Wicked views on stem cell news. Nat Cell Biol. 2009 Jun;11(6):678-9. doi: 10.1038/ncb0609-678. PMID: 19488057.
4: Benetka W, Mehlmer N, Maurer-Stroh S, Sammer M, Koranda M, Neumüller R, Betschinger J, Knoblich JA, Teige M, Eisenhaber F. Experimental testing of predicted myristoylation targets involved in asymmetric cell division and calcium-dependent signalling. Cell Cycle. 2008 Dec;7(23):3709-19. doi: 10.4161/cc.7.23.7176. Epub 2008 Dec 13. Erratum in: Cell Cycle. 2009 Feb 1;8(3):508-9. Erratum in: Cell Cycle. 2021 Feb;20(4):459-460. PMID: 19029837.
3: Neumüller RA, Betschinger J, Fischer A, Bushati N, Poernbacher I, Mechtler K, Cohen SM, Knoblich JA. Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature. 2008 Jul 10;454(7201):241-5. doi: 10.1038/nature07014. Epub 2008 Jun 4. PMID: 18528333; PMCID: PMC2988194.
2: Nizhynska V, Neumueller R, Herbst R. Phosphoinositide 3-kinase acts through RAC and Cdc42 during agrin-induced acetylcholine receptor clustering. Dev Neurobiol. 2007 Jul;67(8):1047-58. doi: 10.1002/dneu.20371. PMID: 17565704.
1: Bowman SK, Neumüller RA, Novatchkova M, Du Q, Knoblich JA. The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division. Dev Cell. 2006 Jun;10(6):731-42. doi: 10.1016/j.devcel.2006.05.005. PMID: 16740476.